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Irbesartan: No knowledge are available in regard to overdosage in people. Nevertheless, day by day doses of 900 mg for eight weeks were being very well tolerated. The most likely manifestations of overdosage are expected to generally be hypotension and tachycardia; bradycardia may also arise from overdose. Irbesartan will not be eradicated by hemodialysis.To get up-to-day details about the remedy of overdosage, a great resource is really a certified regional Poison Regulate Middle. Telephone figures of Qualified Poison Manage Centers are stated while in the Physicians’ Desk Reference (PDR).

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Irbesartan is a particular competitive antagonist of AT1 receptors using a Significantly better affinity (a lot more than 8500-fold) to the AT1 receptor than to the AT2 receptor, and no agonist activity.

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